Invention Grant
- Patent Title: Pyrimidine compounds for the treatment of cancer
- Patent Title (中): 嘧啶化合物治疗癌症
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Application No.: US14384789Application Date: 2013-05-21
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Publication No.: US09567326B2Publication Date: 2017-02-14
- Inventor: Xiaodong Wang , Weihe Zhang , Dmitri Kireev , Dehui Zhang , Andrew McIver
- Applicant: THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Myers Bigel, P.A.
- International Application: PCT/US2013/042033 WO 20130521
- International Announcement: WO2013/177168 WO 20131128
- Main IPC: C07D417/14
- IPC: C07D417/14 ; C07D239/48 ; C07D401/04 ; C07D401/06 ; C07D401/12 ; C07D401/14 ; C07D403/04 ; C07D403/12 ; C07D405/04 ; C07D405/12 ; C07D405/14 ; C07D409/12 ; C07D409/14 ; C07D417/04

Abstract:
Described are compounds of Formula I or Formula II: wherein: ring A is a 5- or 6-membered heteroaryl group; dashed lines are optional double bonds; X is N or O; Y is a carbon atom or an S or N heteroatom in ring A in any suitable location; and substituents are as given herein. Compositions containing the same and methods of using the same in treating cancers such as acute lymphoblastic leukemia are also described.
Public/Granted literature
- US20150038481A1 PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER Public/Granted day:2015-02-05
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