Invention Grant
- Patent Title: Triazolopyridyl compounds as aldosterone synthase inhibitors
- Patent Title (中): 三唑并吡啶基化合物作为醛固酮合酶抑制剂
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Application No.: US14886563Application Date: 2015-10-19
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Publication No.: US09567333B2Publication Date: 2017-02-14
- Inventor: D. Jonathan Bennett , Jaiqiang Cai , Emma Carswell , Andrew Cooke , Scott B. Hoyt , Clare London , John MacLean , Paul Ratcliffe , Jerry Andrew Taylor , Yusheng Xiong , Swapan Kumar Samanta , Bheemashankar A. Kulkarni
- Applicant: Merck Sharp & Dohme Corp.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Janet E. Fair; Anna L. Cocuzzo
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D487/04 ; A61K31/437

Abstract:
This invention relates to triazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.
Public/Granted literature
- US20160039817A1 TRIAZOLOPYRIDYL COMPOUNDS AS ALDOSTERONE SYNTHASE INHIBITORS Public/Granted day:2016-02-11
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