Invention Grant
US09567343B2 Aza-bicyloalkyl ethers and their use as alpha7-nachr agonists
有权
氮杂双环烷基醚及其作为α7 - 纳克激动剂的用途
- Patent Title: Aza-bicyloalkyl ethers and their use as alpha7-nachr agonists
- Patent Title (中): 氮杂双环烷基醚及其作为α7 - 纳克激动剂的用途
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Application No.: US14643275Application Date: 2015-03-10
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Publication No.: US09567343B2Publication Date: 2017-02-14
- Inventor: Dominik Feuerbach , Konstanze Hurth , Timothy John Ritchie , Rochdi Bouhelal
- Applicant: Novartis AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agency: Hoffman Warnick LLC
- Main IPC: C07D453/02
- IPC: C07D453/02 ; C07D487/08 ; A61K31/439 ; A61K31/4439
Abstract:
The present invention relates to 1-aza-bicycloalkyl derivatives of formula I, wherein X is CH2 or a single bond; Y is a group of formula and wherein R has the meanings as defined in the specification, which compounds are alpha 7 nicotinic acetylcholine receptor (nAChR) agonists; to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.
Public/Granted literature
- US20150183794A1 AZA-BICYLOALKYL ETHERS AND THEIR USE AS ALPHA7-NACHR AGONISTS Public/Granted day:2015-07-02
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