Invention Grant
- Patent Title: Notch inhibition in the prevention of vein graft failure
- Patent Title (中): 缺血抑制在预防静脉移植物衰竭
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Application No.: US14855380Application Date: 2015-09-16
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Publication No.: US09567396B2Publication Date: 2017-02-14
- Inventor: Masanori Aikawa , Toshiaki Nakano , Jun-ichiro Koga
- Applicant: The Brigham and Women's Hospital, Inc.
- Applicant Address: DE Essen
- Assignee: Evonik Degussa GmbH
- Current Assignee: Evonik Degussa GmbH
- Current Assignee Address: DE Essen
- Agency: Law Office of: Michael A. Sanzo, LLC
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K31/7088 ; A61K31/713 ; C07K14/705 ; C07K16/18 ; C12N15/113 ; C07K16/28 ; C07K14/475 ; C07K14/52 ; C07K16/22 ; C07K16/24 ; C12N15/11 ; C12N15/13 ; A61K48/00 ; A61K39/00

Abstract:
The present invention is directed to methods of treating a patient to prevent vein graft failure by administering a compound that inhibits the Notch signaling pathway.
Public/Granted literature
- US20160002323A1 Notch Inhibition in the Prevention of Vein Graft Failure Public/Granted day:2016-01-07
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