Invention Grant
- Patent Title: Antibody with specificity for GM-CSF (II)
- Patent Title (中): 抗GM-CSF特异性抗体（II）
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Application No.: US13988498Application Date: 2011-11-17
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Publication No.: US09567398B2Publication Date: 2017-02-14
- Inventor: Laurent Magnenat , Olivier Leger , Charles MacKay , David Georges Zahra
- Applicant: Laurent Magnenat , Olivier Leger , Charles MacKay , David Georges Zahra
- Applicant Address: CH Coinsins, Vaud
- Assignee: MERCK SERONO S.A.
- Current Assignee: MERCK SERONO S.A.
- Current Assignee Address: CH Coinsins, Vaud
- Agency: Arent Fox LLP
- Priority: EP10191664 20101118
- International Application: PCT/EP2011/070375 WO 20111117
- International Announcement: WO2012/066089 WO 20120524
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K39/00 ; C07K16/24 ; C12N15/00
Abstract:
The present invention relates to antibodies with specificity for granulocyte-macrophage colony stimulating factor (GM-CSF). More particularly, the invention relates to humanized monoclonal antibodies that bind specifically to human GM-CSF with high affinity. The invention also relates to nucleic acids encoding the antibodies, vectors for expression of these nucleic acids, and host cells for producing said antibodies. Further, the invention relates to the use of said antibodies in the diagnosis or treatment of autoimmune or inflammatory diseases.
Public/Granted literature
- US20140065163A1 ANTIBODY WITH SPECIFICITY FOR GM-CSF (II) Public/Granted day:2014-03-06
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