Invention Grant
US09567637B2 Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease
有权
HTRA1突变与家族性缺血性脑小血管病变关联
- Patent Title: Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease
- Patent Title (中): HTRA1突变与家族性缺血性脑小血管病变关联
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Application No.: US13265074Application Date: 2010-04-20
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Publication No.: US09567637B2Publication Date: 2017-02-14
- Inventor: Shoji Tsuji , Osamu Onodera
- Applicant: Shoji Tsuji , Osamu Onodera
- Applicant Address: JP Tokyo
- Assignee: THE UNIVERSITY OF TOKYO
- Current Assignee: THE UNIVERSITY OF TOKYO
- Current Assignee Address: JP Tokyo
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- International Application: PCT/JP2010/057323 WO 20100420
- International Announcement: WO2010/123136 WO 20101028
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34
Abstract:
The present invention provides a method of diagnosing a cerebrovascular disease in a human comprising the steps of: (a) measuring a mutation of HTRA1 gene in a test sample from said human; and (b) determining if the mutation of HTRA1 gene in said test sample correlates with a cerebrovascular disease in said human.
Public/Granted literature
- US20120100536A1 ASSOCIATION OF HTRA1 MUTATIONS AND FAMILIAL ISCHEMIC CEREBRAL SMALL-VESSEL DISEASE Public/Granted day:2012-04-26
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