Methods and systems to reconfigure clusters in elastic multi-tenant cloud computing system. An example method includes partitioning a first resource reservation of a first virtual data center between a first cluster and a second cluster and partitioning a second resource reservation of a second virtual data center between the first cluster and the second cluster, and based on the partitioning of the first resource reservation and the second resource reservation, collectively adjusting a first portion of the first resource reservation allotted to the first cluster and a second portion of the second resource reservation allotted to the first cluster in a same reconfiguration operation.