Invention Grant
- Patent Title: Stabilized liquid and lyophilized ADAMTS13 formulations
- Patent Title (中): 稳定的液体和冻干的ADAMTS13制剂
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Application No.: US15145755Application Date: 2016-05-03
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Publication No.: US09572778B2Publication Date: 2017-02-21
- Inventor: Peter Matthiessen , Peter L. Turecek , Hans-Peter Schwarz
- Applicant: Baxalta Incorporated , Baxalta GmbH
- Applicant Address: US IL Bannockburn CH
- Assignee: BAXALTA INCORPORATED,BAXALTA GMBH
- Current Assignee: BAXALTA INCORPORATED,BAXALTA GMBH
- Current Assignee Address: US IL Bannockburn CH
- Agency: Troutman Sanders LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C12N9/00 ; A61K9/19 ; A61K47/02
Abstract:
The present invention relates to formulations of ADAMTS13 with enhanced or desirable properties. As such, the invention provides liquid and lyophilized formulations of ADAMTS13 that are suitable for pharmaceutical administration. Among other aspects, the present invention also provides methods of treating various diseases and conditions related to VWF and/or ADAMTS13 dysfunction in a subject. Also provided herein are kits comprising ADAMTS13 formulations useful for the treatment of various diseases and conditions.
Public/Granted literature
- US20160375111A1 STABILIZED LIQUID AND LYOPHILIZED ADAMTS13 FORMULATIONS Public/Granted day:2016-12-29
Information query
IPC分类:
