Invention Grant
- Patent Title: Engineered polypeptide agents for targeted broad spectrum influenza neutralization
- Patent Title (中): 用于靶向广谱流感中和的工程多肽试剂
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Application No.: US15094522Application Date: 2016-04-08
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Publication No.: US09572861B2Publication Date: 2017-02-21
- Inventor: Ram Sasisekharan , Karthik Viswanathan , Venkataramanan Soundararajan , S. Raguram , Viswanathan Sasisekharan , Vidya Subramanian
- Applicant: Massachusetts Institute of Technology
- Applicant Address: US MA Cambridge
- Assignee: Massachusetts Institute of Technology
- Current Assignee: Massachusetts Institute of Technology
- Current Assignee Address: US MA Cambridge
- Agency: Choate, Hall & Stewart LLP
- Agent Brenda Herschbach Jarrell; Cassandra Gianna Luca
- Main IPC: C07K14/00
- IPC: C07K14/00 ; C07K14/005 ; G01N33/569 ; A61K38/00 ; A61K38/16 ; C12N7/00 ; A61K9/00

Abstract:
The present invention provides novel agents for broad spectrum influenza neutralization. The present invention provides agents for inhibiting influenza infection by bind to the influenza virus and/or hemagglutinin (HA) polypeptides and/or HA receptors, and reagents and methods relating thereto. The present invention provides a system for analyzing interactions between infolds and the interaction partners that bind to them.
Public/Granted literature
- US20160317612A1 ENGINEERED POLYPEPTIDE AGENTS FOR TARGETED BROAD SPECTRUM INFLUENZA NEUTRALIZATION Public/Granted day:2016-11-03
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