Invention Grant
US09572873B2 Method of inducing a T lymphocyte response using T-cell immunogens derived from anti-viral proteins
有权
使用衍生自抗病毒蛋白的T细胞免疫原诱导T淋巴细胞应答的方法
- Patent Title: Method of inducing a T lymphocyte response using T-cell immunogens derived from anti-viral proteins
- Patent Title (中): 使用衍生自抗病毒蛋白的T细胞免疫原诱导T淋巴细胞应答的方法
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Application No.: US14793534Application Date: 2015-07-07
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Publication No.: US09572873B2Publication Date: 2017-02-21
- Inventor: Douglas F. Nixon , Stephane Champiat , Keith Garrison
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic Field & Francis, LLP
- Agent Paula A. Borden
- Main IPC: A61K39/21
- IPC: A61K39/21 ; A61K39/12 ; C07K7/06 ; C07K7/08 ; C07K14/16 ; C07H21/00 ; A61K39/00 ; C07K14/005 ; A61K38/10 ; A61K38/08 ; A61K38/16
Abstract:
Isolated polypeptides related to endogenous anti-viral polypeptides; and compositions, including immunogenic compositions, comprising a subject isolated polypeptide are disclosed herein. A subject isolated polypeptide comprises an amino acid sequence having substantial amino acid sequence identity to a contiguous stretch of amino acids of one or more endogenous anti-viral polypeptides, wherein the endogenous anti-viral polypeptides are polypeptides subject to proteolytic degradation as a result of the activity of one or more viral proteins. Also provided are diagnostic and treatment methods using the subject isolated polypeptides and compositions.
Public/Granted literature
- US20160151470A1 T-CELL IMMUNOGENS DERIVED FROM ANTI-VIRAL PROTEINS AND METHODS OF USING SAME Public/Granted day:2016-06-02
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