Invention Grant
- Patent Title: Naphthalene derivative
- Patent Title (中): 萘衍生物
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Application No.: US13813190Application Date: 2011-07-28
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Publication No.: US09573887B2Publication Date: 2017-02-21
- Inventor: Akira Kakizuka , Seiji Hori , Toshiyuki Shudo , Tomohiro Fuchigami
- Applicant: Akira Kakizuka , Seiji Hori , Toshiyuki Shudo , Tomohiro Fuchigami
- Applicant Address: JP Osaka JP Kyoto
- Assignee: Daito Chemix Corporation,Kyoto University
- Current Assignee: Daito Chemix Corporation,Kyoto University
- Current Assignee Address: JP Osaka JP Kyoto
- Agency: Morgan, Lewis & Bockius LLP
- Priority: JP2010-172467 20100730
- International Application: PCT/JP2011/067320 WO 20110728
- International Announcement: WO2012/014994 WO 20120202
- Main IPC: C07D213/77
- IPC: C07D213/77 ; A61K31/4418 ; C07D213/76 ; C07C245/10 ; C07C309/47 ; C07C323/48 ; C07D215/38 ; C07D217/14 ; C07D333/38 ; C07D401/04 ; C07D401/12 ; C07D405/04 ; C07D405/12 ; C07D409/04 ; C07D409/14 ; C07D413/04 ; C07D213/81 ; C07D213/30 ; C07D213/42 ; C07D401/10 ; C07D405/10 ; C07D409/10
Abstract:
The present invention provides compounds which can regulate VCP activity. The present invention provides the compound of formula (I) (R is as defined in the description) or oxides, esters, prodrugs, pharmaceutically acceptable salts or solvates thereof. The compounds can regulate VCP activity, and thus are useful for treating VCP-mediated diseases such as neurodegenerative diseases.
Public/Granted literature
- US20130184241A1 Naphthalene Derivative Public/Granted day:2013-07-18
Information query
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