Invention Grant
- Patent Title: Polymorphs of deuterated omega-diphenylurea or salts thereof
- Patent Title (中): 氘代ω-二苯基脲或其盐的多晶型物
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Application No.: US14415340Application Date: 2013-07-16
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Publication No.: US09573900B2Publication Date: 2017-02-21
- Inventor: Weidong Feng
- Applicant: Suzhou Zelgen Biopharmaceuticals Co., Ltd.
- Applicant Address: CN Jiangsu
- Assignee: Suzhou Zelgen Biopharmaceutical Co., Ltd.
- Current Assignee: Suzhou Zelgen Biopharmaceutical Co., Ltd.
- Current Assignee Address: CN Jiangsu
- Agency: Panitch Schwarze Belisario & Nadel LLP
- Priority: CN201210249796 20120718
- International Application: PCT/CN2013/079469 WO 20130716
- International Announcement: WO2014/012480 WO 20140123
- Main IPC: C07D213/81
- IPC: C07D213/81 ; A61K31/44

Abstract:
The invention relates to polymorphs of deuterated omega-diphenylurea or salts thereof. In particular, the invention provides polymorphs of 4-(4-{3-[4-chloro-3-(trifluoromethyl)phenyl)-ureido]-phenoxy}-2-(N-1′,1′,1′-trideutero-methyl)picolinamide or its salt, namely, polymorphs of the compound as shown in formula (I) or its salt. The polymorphs are suited for preparing the pharmaceutical composition used for inhibiting phosphokinase (such as raf kinases).
Public/Granted literature
- US20150266823A1 POLYMORPHS OF DEUTERATED OMEGA-DIPHENYLUREA OR SALTS THEREOF Public/Granted day:2015-09-24
Information query
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