Invention Grant
US09573919B2 Peroxisome proliferator-activated receptor (PPAR) activator, and drugs, supplements, functional foods and food additives using the same 有权
过氧化物酶体增殖物激活受体(PPAR)激活剂,以及药物,补充剂,功能食品和使用其的食品添加剂

  • Patent Title: Peroxisome proliferator-activated receptor (PPAR) activator, and drugs, supplements, functional foods and food additives using the same
  • Patent Title (中): 过氧化物酶体增殖物激活受体(PPAR)激活剂,以及药物,补充剂,功能食品和使用其的食品添加剂
  • Application No.: US11800637
    Application Date: 2007-05-07
  • Publication No.: US09573919B2
    Publication Date: 2017-02-21
  • Inventor: Takao Sasaki
  • Applicant: Takao Sasaki
  • Applicant Address: JP Kyoto
  • Assignee: ARKRAY, Inc.
  • Current Assignee: ARKRAY, Inc.
  • Current Assignee Address: JP Kyoto
  • Agency: Morgan, Lewis & Bockius LLP
  • Priority: JP2004-324015 20041108
  • Main IPC: C07D311/30
  • IPC: C07D311/30 A61K31/352 A61K36/752
Peroxisome proliferator-activated receptor (PPAR) activator, and drugs, supplements, functional foods and food additives using the same
Abstract:
The present invention provides a peroxisome proliferator-activated receptor (PPAR) activator, which is free from the problem of side effects, can be taken over a long term and has no characteristics taste. Nobiletin is employed as a PPAR activator. Nobiletin has an excellent PPAR activity and has an excellent adiponectin secretion-promoting effect, and is contained in a large amount in citrus fruits, in particular, in Shiikuwasha (Citrus depressa HAYATA) indigenous to Okinawa (Japan). Since citrus fruits have been consumed for many years, the safety of nobiletin has been proven and besides, nobiletin has a low calorie content. Therefore, it can be taken over a long term. Moreover, because of being tasteless and odorless, nobiletin would not damage the unique taste of a food when added thereto. Therefore, it can be added to foods and taken.
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