Invention Grant
US09573921B2 Substituted N, N-dimethylaminoalkyl ethers of isoflavanone oximes as H1-receptor antagonists 有权
取代异黄烷酮肟的N,N-二甲基氨基烷基醚作为H1-受体拮抗剂

Substituted N, N-dimethylaminoalkyl ethers of isoflavanone oximes as H1-receptor antagonists
Abstract:
The present invention relates to compounds of formula (I), and salts thereof and the pharmaceutical composition containing them in treatment of various diseases, as allergic rhinitis where R1 and R2 are, independently, hydrogen, halogen, C1_3 alkyl or C1-3alkoxy; R3 is phenyl optionally substituted by R4 and R5 which are, independently hydrogen, halogen, C1-3 alkyl, C1-3-alkoxy, fluoro-, difluoro- and trifluoromethyl, nitrile group, N,N-diC1-3alkyl-amide, carboC1-3 alkoxy or C1-3alkylsulphone groups; R3 is pyridyl group containing nitrogen at various positions in the benzene ring, n is one of the integers 1 or 2.
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