Invention Grant
- Patent Title: Muscarinic M1 receptor agonists
- Patent Title (中): 毒蕈碱M1受体激动剂
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Application No.: US14941328Application Date: 2015-11-13
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Publication No.: US09573929B2Publication Date: 2017-02-21
- Inventor: Miles Stuart Congreve , Giles Albert Brown , Julie Elaine Cansfield , Benjamin Gerald Tehan
- Applicant: Heptares Therapeutics Limited
- Applicant Address: GB Welwyn Garden City, Hertfordshire
- Assignee: Heptares Therapeutics Limited
- Current Assignee: Heptares Therapeutics Limited
- Current Assignee Address: GB Welwyn Garden City, Hertfordshire
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- Main IPC: A61K31/55
- IPC: A61K31/55 ; C07D401/04 ; C07D211/06 ; C07D401/14

Abstract:
This invention relates to compounds that are agonists of the muscarinic M1 receptor and which are useful in the treatment of muscarinic M1 receptor mediated diseases. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula I, where n is 1 or 2; p is 0, 1 or 2; q is 0, 1 or 2; and R1-R6 are as defined herein.
Public/Granted literature
- US20160068508A1 Muscarinic M1 Receptor Agonists Public/Granted day:2016-03-10
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