Invention Grant
US09573976B2 Antagonist for (pro)renin receptor for the treatment of hypertension and diabetes
有权
（pro）肾素受体拮抗剂用于治疗高血压和糖尿病
- Patent Title: Antagonist for (pro)renin receptor for the treatment of hypertension and diabetes
- Patent Title (中): （pro）肾素受体拮抗剂用于治疗高血压和糖尿病
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Application No.: US14429733Application Date: 2013-09-18
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Publication No.: US09573976B2Publication Date: 2017-02-21
- Inventor: Yumei Feng
- Applicant: University of Utah
- Applicant Address: US UT Salt Lake City
- Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
- Current Assignee: UNIVERSITY OF UTAH RESEARCH FOUNDATION
- Current Assignee Address: US UT Salt Lake City
- Agency: Ballard Spahr LLP
- International Application: PCT/US2013/060437 WO 20130918
- International Announcement: WO2014/047194 WO 20140327
- Main IPC: C07K7/08
- IPC: C07K7/08 ; C07K7/06 ; C07K14/00 ; C07K14/47 ; C07K14/705 ; A61K38/00 ; A61K9/00
Abstract:
Methods and compositions for increasing a plant's resistance to an insect pest such as the corn rootworm are provided. Methods are provided for overexpression of Crw2, or variants thereof, in a host plant or plant cell to increase resistance to an insect pest in a plant such as maize. Methods are also provided for identifying variants of Crw2 that when incorporated into a plant via transgenic or traditional breeding means increase resistance to an insect pest in a plant such as maize. Also provided are methods for increasing resistance by overexpressing Crw1 and Crw2.
Public/Granted literature
- US20150252074A1 Antagonist for (Pro)Renin Receptor for the Treatment of Hypertension and Diabetes Public/Granted day:2015-09-10
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