Invention Grant
- Patent Title: Optimized anti-CD30 antibodies
- Patent Title (中): 优化抗CD30抗体
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Application No.: US13163465Application Date: 2011-06-17
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Publication No.: US09574006B2Publication Date: 2017-02-21
- Inventor: Gregory Alan Lazar , John R. Desjarlais , Philip W. Hammond , David F. Carmichael , Bao-lu Chen , Seung Y. Chu , Sher Bahadur Karki , Lori Kunkel
- Applicant: Gregory Alan Lazar , John R. Desjarlais , Philip W. Hammond , David F. Carmichael , Bao-lu Chen , Seung Y. Chu , Sher Bahadur Karki , Lori Kunkel
- Applicant Address: US CA Monrovia
- Assignee: Xencor, Inc.
- Current Assignee: Xencor, Inc.
- Current Assignee Address: US CA Monrovia
- Agency: Polsinelli PC
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28
Abstract:
An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcγR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
Public/Granted literature
- US20120014943A1 Optimized Anti-CD30 Antibodies Public/Granted day:2012-01-19
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