Invention Grant
- Patent Title: Method for producing three-dimensional monolithic microfluidic devices
- Patent Title (中): 三维单片微流体装置的制造方法
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Application No.: US14123315Application Date: 2012-05-31
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Publication No.: US09574172B2Publication Date: 2017-02-21
- Inventor: Cristina Lenardi , Alessandro Tocchio , Federico Martello
- Applicant: Cristina Lenardi , Alessandro Tocchio , Federico Martello
- Applicant Address: IT Milan
- Assignee: TENSIVE S.R.L.
- Current Assignee: TENSIVE S.R.L.
- Current Assignee Address: IT Milan
- Agency: Abelman, Frayne & Schwab
- Priority: ITMI2011A0995 20110531
- International Application: PCT/IB2012/052732 WO 20120531
- International Announcement: WO2012/164512 WO 20121206
- Main IPC: C12N5/00
- IPC: C12N5/00 ; G03F7/00 ; B29C45/00 ; B81C1/00 ; B82Y10/00 ; B82Y40/00

Abstract:
A method is described for producing a microfluidic device (19), which comprises the phases of producing a three-dimensional template (15) of geometry equal to the channelings that is desired to obtain in the device; inserting the template in the desired position into a mold (16), keeping it suspended by at least one of its end; coating said template by immersion in (or deposition of) a material in the liquid phase (or dissolved or dispersed in a solvent) capable of solidifying by means of a chemical reaction or physical transformation, forming a material constituting the body of the final device; and selectively removing the three-dimensional template. In a variant of the method, useful for the production of scaffolds to be inserted into the human body, a porogenic material is added to the liquid precursor or to the precursor solution, such that the material of the solid matrix is characterized by a continuous structure of pores into which it is possible to insert live cells.
Public/Granted literature
- US20140106454A1 METHOD FOR PRODUCING THREE-DIMENSIONAL MONOLITHIC MICROFLUIDIC DEVICES Public/Granted day:2014-04-17
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