Methods and device are disclosed for data retrieval. At first images and reports are analyzed by respective parser units to detect both structures and text passages that are related to respective structures and text passages of a knowledge data-base. The detected structures and text passages are stored together with a unique resource located that identifies the respective structure and/or text passage at the knowledge database in a semantic annotation database. In addition a feature extraction can be performed to provide specific features of the images and/or regions of the images, whereby the features are stored in an image feature database. Finally an input query can ask questions that are used to provide a result to the query based on the semantic annotation database and the image feature database. The methods and devices may be used for data preparation and data retrieval of medical images and associated medical reports.