Embodiments of the present invention provide a method and an apparatus for determining clock desynchronization. The method includes: detecting a cell with exceptional IN information or power information among all cells of base stations throughout a network according to network measurement data sent by a base station, and using the cell as a first cell, where the network measurement data includes interference and noise (IN) information or power information; and sorting the first cell according to different types of exceptions of the IN information or power information, so as to determine that one or more of the base stations throughout the network are in clock desynchronization.