Invention Grant
US09579404B2 Lanthanoid complex capsule and particle contrast agents, methods of making and using thereof
有权
镧系元素复合物胶囊和颗粒造影剂，其制备和使用方法
- Patent Title: Lanthanoid complex capsule and particle contrast agents, methods of making and using thereof
- Patent Title (中): 镧系元素复合物胶囊和颗粒造影剂，其制备和使用方法
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Application No.: US14492749Application Date: 2014-09-22
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Publication No.: US09579404B2Publication Date: 2017-02-28
- Inventor: Marc Anton Walters
- Applicant: New York University
- Applicant Address: US NY New York
- Assignee: New York University
- Current Assignee: New York University
- Current Assignee Address: US NY New York
- Agency: LeClairRyan, a Professional Corporation
- Main IPC: A61K49/00
- IPC: A61K49/00 ; A61K49/18 ; A61K49/10 ; A61K49/12 ; A61K9/51 ; C07D257/02 ; C07F5/00
Abstract:
The invention relates to compositions of DOTA derivative compounds, lanthanoid-DOTA derivative molecular complex, and lanthanoid-complex encapsulated solid lipid particles or capsules, and methods of making and using the compositions. The solid lipid particles or capsules contain micelle cores stabilized by a hyperbranched polymer shell based from a crosslinked DOTA derivative compound or crosslinked lanthanoid-DOTA derivative complex. These solid lipid particles or capsules can be used in various applications, such as contrast agents or drug delivery vehicles.
Public/Granted literature
- US20150071863A1 LANTHANOID COMPLEX CAPSULE AND PARTICLE CONTRAST AGENTS, METHODS OF MAKING AND USING THEREOF Public/Granted day:2015-03-12
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