Embodiments of the claimed subject matter provide a radiation therapy system for the acquisition of volumetric imaging with advanced trajectories. Embodiments include a device for applying diagnostic and therapeutic radiation to a target volume disposed in a patient subject, wherein volumetric imaging is acquired with advanced trajectories without displacing the patient subject. In one embodiment, a radiation therapy device is provided comprising: a gantry with a radiation source and a plurality of independent robotic arms mounted to the gantry, wherein an X-ray source is attached to an end of one robotic arm; and an imager attached to an end of another second robotic arm.