Invention Grant
US09580744B2 Method and apparatus for applying continuous flow and uniform temperature to generate thermal melting curves in a microfluidic device
有权
用于在微流体装置中施加连续流动和均匀温度以产生热解链曲线的方法和装置
- Patent Title: Method and apparatus for applying continuous flow and uniform temperature to generate thermal melting curves in a microfluidic device
- Patent Title (中): 用于在微流体装置中施加连续流动和均匀温度以产生热解链曲线的方法和装置
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Application No.: US14331886Application Date: 2014-07-15
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Publication No.: US09580744B2Publication Date: 2017-02-28
- Inventor: Ivor T. Knight , Deborah J. Boles
- Applicant: Canon U.S. Life Sciences, Inc.
- Applicant Address: US MD Rockville
- Assignee: Canon U.S. Life Sciences, Inc.
- Current Assignee: Canon U.S. Life Sciences, Inc.
- Current Assignee Address: US MD Rockville
- Agency: Rothwell, Figg, Ernst & Manbeck, P.C.
- Main IPC: C12P19/34
- IPC: C12P19/34 ; C12Q1/68 ; B01L3/00 ; B01L7/00
Abstract:
The present invention provides a method for performing thermal melt analysis using a microfluidic device, the method comprising providing a microfluidic device having at least one microfluidic channel, introducing fluid comprising into the at least one microfluidic channel, continuously flowing the fluid through the at least one microfluidic channel while varying the temperature of the entire fluid stream as it moves through the at least one microfluidic channel by uniformly heating the entire fluid stream, and measuring, while continuously flowing the fluid through the at least one microfluidic channel, a detectable property emanating from the fluid.
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