Invention Grant
US09580752B2 Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
有权
预测需要结肠切除术的医疗屈光性溃疡性结肠炎（MR-UC）的方法
- Patent Title: Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
- Patent Title (中): 预测需要结肠切除术的医疗屈光性溃疡性结肠炎（MR-UC）的方法
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Application No.: US13140874Application Date: 2009-12-24
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Publication No.: US09580752B2Publication Date: 2017-02-28
- Inventor: Jerome I. Rotter , Kent D. Taylor , Stephan R. Targan , Talin Haritunians , Dermot P. McGovern , Xiuqing Guo
- Applicant: Jerome I. Rotter , Kent D. Taylor , Stephan R. Targan , Talin Haritunians , Dermot P. McGovern , Xiuqing Guo
- Applicant Address: US CA Los Angeles
- Assignee: CEDARS-SINAI MEDICAL CENTER
- Current Assignee: CEDARS-SINAI MEDICAL CENTER
- Current Assignee Address: US CA Los Angeles
- Agency: Nixon Peabody LLP
- International Application: PCT/US2009/069531 WO 20091224
- International Announcement: WO2010/075579 WO 20100701
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
Disclosed are methods of predicting the development of medically refractory ulcerative colitis (MR-UC) in a patient In one embodiment, disclosed is a method of prognosing ulcerative colitis in an individual by determining the presence or absence of one or more risk variants, where the presence of one or more risk variants is indicative of a severe and/or aggressive form of ulcerative colitis. In another embodiment, the severe form of ulcerative colitis is indicative of MR-UC.
Public/Granted literature
- US20120053131A1 METHODS OF PREDICTING MEDICALLY REFRACTIVE ULCERATIVE COLITIS (MR-UC) REQUIRING COLECTOMY Public/Granted day:2012-03-01
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