A surgical clip applier comprises a first arm (12) and a second arm (14) pivotable relative to each other and defining proximal ends (16, 18) for manually controlling the applier, and distal ends (26, 28); jaws (30) positioned between the distal ends such (26, 28) that pivot of the first arm (12) relative to the second arm (14) opens and closes the jaws (30); and a setting element (32) movably mounted in one (12) of the first arm and the second arm and extending into contact with the other (14) of the first arm and the second arm to define a maximum open position of the first arm (12) relative to the second arm (14), and wherein a change of position of the setting element (32) adjusts the maximum open position.