A method of treating venous insufficiency and lymphedema in an individual by placing pulsatile, localized pressure or compression on deep veins and subcutaneous tissue by inflating and deflating volume-changing members implanted within the individual. A method of potentiating venous circulation, by placing pulsatile, localized pressure that compresses the deep veins by expanding and contracting volume-changing members located between the fascia and muscular compartment, such that the increase in volume from the volume-changing members is transferred to deep veins, and augmenting the effects of muscle contractions around the deep veins and improving blood circulation. A method of potentiating lymphatic circulation. A method of potentiating venous and lymphatic circulation. A pulsatile pressure implant including at least one volume-changing member in electronic connection with an electronic-controlled microprocessor.