Invention Grant
US09585853B2 Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
有权
使用1,3-二苯基丙-2-烯-1-酮衍生物治疗肝脏疾病
- Patent Title: Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
- Patent Title (中): 使用1,3-二苯基丙-2-烯-1-酮衍生物治疗肝脏疾病
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Application No.: US14933335Application Date: 2015-11-05
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Publication No.: US09585853B2Publication Date: 2017-03-07
- Inventor: Raphael Darteil , Rémy Hanf , Dean Hum , Ingrid Dufour
- Applicant: GENFIT
- Applicant Address: FR Loos
- Assignee: GENFIT
- Current Assignee: GENFIT
- Current Assignee Address: FR Loos
- Agency: Nixon & Vanderhye P.C.
- Priority: EP09306146 20091126
- Main IPC: A61K31/192
- IPC: A61K31/192 ; C07C321/26 ; A61K45/06 ; A61K38/28 ; A61K31/155 ; A61K31/216 ; A61K31/222 ; A61K31/381 ; A61K31/426

Abstract:
The invention provides 1,3-diphenylprop-2-en-1-one derivatives and pharmaceutical compositions comprising the same for treating liver disorders, in particular those requiring the reduction of plasma level of biochemical markers such as aminotransferases. The 1,3-diphenylprop-2-en-1-one derivatives of General Formula (I) have hepatoprotective properties and can be used in methods for treating liver disorders involving the pathological disruption, inflammation, degeneration, and/or proliferation of liver cells, such as liver fibrosis or fatty liver disease.
Public/Granted literature
- US20160051501A1 USE OF 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES FOR TREATING LIVER DISORDERS Public/Granted day:2016-02-25
Information query
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