Invention Grant
- Patent Title: Pyrimidinedione compounds
- Patent Title (中): 嘧啶二酮化合物
-
Application No.: US14883152Application Date: 2015-10-14
-
Publication No.: US09585883B2Publication Date: 2017-03-07
- Inventor: Johan Oslob , Robert Anderson , Danielle Aubele , Marc Evanchik , Jonathan Charles Fox , Brian Kane , Puping Lu , Robert McDowell , Hector Rodriguez , Yonghong Song , Arvinder Sran
- Applicant: MyoKardia, Inc.
- Applicant Address: US CA South San Francisco
- Assignee: MYOKARDIA, INC.
- Current Assignee: MYOKARDIA, INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Main IPC: A61K31/513
- IPC: A61K31/513 ; A61K45/06 ; C07D239/545 ; C07D239/553 ; C07D401/04 ; C07D403/04 ; C07D403/12 ; C07D405/04 ; C07D405/12 ; C07D413/04 ; C07D401/12 ; C07D413/12

Abstract:
Provided are novel pyrimidine dione compounds and pharmaceutically acceptable salts thereof, that are useful for the treatment of hypertrophic cardiomyopathy (HCM) and conditions associated with left ventricular hypertrophy or diastolic dysfunction. The synthesis and characterization of the compounds and pharmaceutically acceptable salts thereof, are described, as well as methods for treating HCM and other forms of heart disease.
Public/Granted literature
- US20160030428A1 PYRIMIDINEDIONE COMPOUNDS Public/Granted day:2016-02-04
Information query
IPC分类: