Invention Grant
- Patent Title: Methods and compositions for modulating Tau levels
- Patent Title (中): 调节Tau水平的方法和组合物
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Application No.: US14697156Application Date: 2015-04-27
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Publication No.: US09585907B2Publication Date: 2017-03-07
- Inventor: Li Gan
- Applicant: THE J. DAVID GLADSTONE INSTITUTES
- Applicant Address: US CA San Francisco
- Assignee: The J. David Gladstone Institutes
- Current Assignee: The J. David Gladstone Institutes
- Current Assignee Address: US CA San Francisco
- Agency: Bozicevic, Field & Francis LLP
- Agent Michael B. Rubin
- Main IPC: A61K31/55
- IPC: A61K31/55 ; G01N33/542 ; C12N5/02 ; A61K31/713 ; A61K31/551 ; A61K38/50 ; G01N33/68 ; A61K9/00 ; A61K31/4155 ; G01N33/556

Abstract:
Methods and agents for reducing a level of an acetylated Tau polypeptide in a cell are provided. Methods for treating a tauopathy in an individual are also provided. Also provided is a method for diagnosing a cognitive impairment disorder in an individual. Methods for identifying an agent suitable for treating a tauopathy are also provided.
Public/Granted literature
- US20160015733A1 METHODS AND COMPOSITIONS FOR MODULATING TAU LEVELS Public/Granted day:2016-01-21
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