Invention Grant
- Patent Title: Use of polymeric excipients for lyophilization or freezing of particles
- Patent Title (中): 使用聚合物赋形剂冻干或冷冻颗粒
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Application No.: US14362382Application Date: 2012-12-13
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Publication No.: US09585960B2Publication Date: 2017-03-07
- Inventor: Willard Foss , Rajesh Shinde
- Applicant: Abraxis BioScience, LLC
- Applicant Address: US CA Los Angeles
- Assignee: ABRAXIS BIOSCIENCE, LLC
- Current Assignee: ABRAXIS BIOSCIENCE, LLC
- Current Assignee Address: US CA Los Angeles
- Agency: Morrison & Foerster LLP
- International Application: PCT/US2012/069585 WO 20121213
- International Announcement: WO2013/090634 WO 20130620
- Main IPC: A61L29/02
- IPC: A61L29/02 ; A61K47/32 ; A61K9/19 ; A61K31/337 ; A61K9/00 ; A61K9/51 ; A61K9/50 ; A61K47/26 ; A61K9/10

Abstract:
Provided herein are use of polymeric excipients, specifically polyvinyl alcohols, optionally in conjunction with sugars, as cryoprotectants to prevent aggregation of PEG-containing particles. Also provided are PEG-containing particles comprising such polymeric excipients.
Public/Granted literature
- US20150157722A1 USE OF POLYMERIC EXCIPIENTS FOR LYOPHILIZATION OR FREEZING OF PARTICLES Public/Granted day:2015-06-11
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