Invention Grant
- Patent Title: Nitroxyl donors with improved therapeutic index
- Patent Title (中): 具有改善的治疗指数的硝基供体
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Application No.: US14880173Application Date: 2015-10-09
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Publication No.: US09586896B2Publication Date: 2017-03-07
- Inventor: Vincent Jacob Kalish , Frederick Arthur Brookfield , Stephen Martin Courtney , Lisa Marie Frost , John P. Toscano
- Applicant: Cardioxyl Pharmaceuticals, Inc.
- Applicant Address: US NC Chapel Hill
- Assignee: Cardioxyl Pharmaceuticals, Inc.
- Current Assignee: Cardioxyl Pharmaceuticals, Inc.
- Current Assignee Address: US NC Chapel Hill
- Agency: Byrne Poh LLP
- Agent Nina R. Horan
- Main IPC: C07C317/14
- IPC: C07C317/14 ; A61K31/24 ; A61K47/40 ; A61K31/222 ; A61K31/18 ; C07D307/64 ; A61K31/341 ; A61K31/255 ; A61K31/343 ; A61K31/381 ; A61K31/404 ; A61K31/42 ; A61K31/433 ; A61K31/4436 ; A61K31/5377 ; A61K31/538 ; A61K47/12
Abstract:
The disclosed subject matter provides N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating heart failure.
Public/Granted literature
- US20160031807A1 NITROXYL DONORS WITH IMPROVED THERAPEUTIC INDEX Public/Granted day:2016-02-04
Information query
