Invention Grant
US09586910B2 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide
有权
3,5-二氨基-6-氯-N-（N-（4-（4-（2-（己基（2,3,4,5,6-五羟基己基）氨基）乙氧基）苯基）丁基）氨基甲脒基）吡嗪 -2-甲酰胺
- Patent Title: 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(hexyl(2,3,4,5,6-pentahydroxyhexyl)amino)ethoxy)phenyl)butyl)carbamimidoyl)pyrazine-2-carboxamide
- Patent Title (中): 3,5-二氨基-6-氯-N-（N-（4-（4-（2-（己基（2,3,4,5,6-五羟基己基）氨基）乙氧基）苯基）丁基）氨基甲脒基）吡嗪 -2-甲酰胺
-
Application No.: US14132194Application Date: 2013-12-18
-
Publication No.: US09586910B2Publication Date: 2017-03-07
- Inventor: Michael R. Johnson
- Applicant: Parion Sciences, Inc.
- Applicant Address: US NC Durham
- Assignee: Parion Sciences, Inc.
- Current Assignee: Parion Sciences, Inc.
- Current Assignee Address: US NC Durham
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K31/4965
- IPC: A61K31/4965 ; C07D241/26 ; C07D239/48 ; A61K45/06 ; C07D241/34
Abstract:
The present invention relates to the compound of the formula: or pharmaceutically acceptable salts thereof, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, acute and chronic bronchitis, cystic fibrosis, emphysema, and pneumonia.
Public/Granted literature
Information query
