Invention Grant
US09586911B2 Arylalkyl- and aryloxyalkyl-substituted epthelial sodium channel blocking compounds
有权
芳基烷基和芳氧基烷基取代的上皮钠通道阻断化合物
- Patent Title: Arylalkyl- and aryloxyalkyl-substituted epthelial sodium channel blocking compounds
- Patent Title (中): 芳基烷基和芳氧基烷基取代的上皮钠通道阻断化合物
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Application No.: US14577098Application Date: 2014-12-19
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Publication No.: US09586911B2Publication Date: 2017-03-07
- Inventor: Michael R. Johnson
- Applicant: PARION SCIENCES, INC.
- Applicant Address: US NC Durham
- Assignee: Parion Sciences, Inc.
- Current Assignee: Parion Sciences, Inc.
- Current Assignee Address: US NC Durham
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K31/4965
- IPC: A61K31/4965 ; C07D241/32 ; A61K45/06 ; A61K31/047 ; A61K33/14
Abstract:
The present invention relates to the compound of the formula: or pharmaceutically acceptable salts thereof, as well as compositions containing the same, processes for the preparation of the same, and therapeutic methods of use therefore in promoting hydration of mucosal surfaces and the treatment of diseases including chronic obstructive pulmonary disease (COPD), asthma, bronchiectasis, acute and chronic bronchitis, cystic fibrosis, emphysema, and pneumonia.
Public/Granted literature
- US20150166488A1 ARYLALKYL- AND ARYLOXYALKYL-SUBSTITUTED EPTHELIAL SODIUM CHANNEL BLOCKING COMPOUNDS Public/Granted day:2015-06-18
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