Invention Grant
- Patent Title: 2-pyridyloxy-4-methyl orexin receptor antagonists
- Patent Title (中): 2-吡啶氧基-4-甲基orexin受体拮抗剂
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Application No.: US15103079Application Date: 2014-12-04
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Publication No.: US09586934B2Publication Date: 2017-03-07
- Inventor: Scott D. Kuduk , Jason W. Skudlarek
- Applicant: MERCK SHARP & DOHME CORP.
- Applicant Address: US NJ Rahway
- Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; John C. Todaro
- International Application: PCT/US2014/068475 WO 20141204
- International Announcement: WO2015/088865 WO 20150618
- Main IPC: C07D401/12
- IPC: C07D401/12 ; C07D401/14 ; C07D409/14 ; C07D413/14 ; A61K31/4545 ; A61K31/497
Abstract:
The present invention is directed to 2-pyridyloxy-4-methyl compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyloxy-4-methyl compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Public/Granted literature
- US20160368898A1 2-PYRIDYLOXY-4-METHYL OREXIN RECEPTOR ANTAGONISTS Public/Granted day:2016-12-22
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