Invention Grant
- Patent Title: sGC stimulators
- Patent Title (中): sGC刺激剂
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Application No.: US15215628Application Date: 2016-07-21
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Publication No.: US09586937B2Publication Date: 2017-03-07
- Inventor: Takashi Nakai , Joel Moore , Nicholas Robert Perl , Rajesh R. Iyengar , Ara Mermerian , G-Yoon Jamie Im , Thomas Wai-Ho Lee , Colleen Hudson , Glen Robert Rennie , James Jia , Paul Allan Renhowe , Timothy Claude Barden , Xiang Y. Yu , James Edward Sheppeck , Karthik Iyer , Joon Jung , George Todd Milne , Kimberly Kafadar Long , Mark G. Currie
- Applicant: Ironwood Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: IRONWOOD PHARMACEUTICALS, INC.
- Current Assignee: IRONWOOD PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Cambridge
- Agency: Heslin, Rothenberg, Farley & Mesiti, P.C.
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D413/14 ; C07D491/107 ; C07D417/14 ; C07D401/14 ; A61K31/506 ; A61K31/5377 ; C07D471/10 ; C07D487/10 ; A61K31/541 ; A61K31/55 ; C07D471/08 ; C07D487/04 ; C07D498/04 ; A61K31/519 ; A61K31/517
Abstract:
Compounds of Formulae I′ and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.
Public/Granted literature
- US20160347738A1 sGC STIMULATORS Public/Granted day:2016-12-01
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