Invention Grant
US09586942B2 Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
有权
氨基四氢化萘和氨基茚满衍生物，含有它们的药物组合物及其在治疗中的应用
- Patent Title: Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
- Patent Title (中): 氨基四氢化萘和氨基茚满衍生物，含有它们的药物组合物及其在治疗中的应用
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Application No.: US14517205Application Date: 2014-10-17
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Publication No.: US09586942B2Publication Date: 2017-03-07
- Inventor: Wilhelm Amberg , Frauke Pohlki , Udo Lange , Ying Wang , Jason Brewer , Anil Vasudevan , Yanbin Lao , Charles Hutchins , Hongyu Zhao , Huan-Qiu Li
- Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
- Applicant Address: DE Wiesbaden US IL North Chicago
- Assignee: AbbVie Deutschland GmbH & Co. KG,AbbVie Inc.
- Current Assignee: AbbVie Deutschland GmbH & Co. KG,AbbVie Inc.
- Current Assignee Address: DE Wiesbaden US IL North Chicago
- Agency: Neal, Gerber & Eisenberg LLP
- Main IPC: C07D403/12
- IPC: C07D403/12 ; C07D401/12 ; C07D233/42 ; C07D207/273 ; C07D205/04 ; C07D403/14 ; C07D403/10 ; C07D405/14 ; A61K31/4164
Abstract:
The present invention relates to aminotetraline and aminoindane derivatives of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such aminotetraline and aminoindane derivatives, and the use of such aminotetraline and aminoindane derivatives for therapeutic purposes. The aminotetraline and aminoindane derivatives are GlyT1 inhibitors.
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