Invention Grant
- Patent Title: 2-pyridyloxy-3-ester-4-nitrile orexin receptor antagonists
- Patent Title (中): 2-吡啶氧基-3-酯-4-腈食欲素受体拮抗剂
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Application No.: US14436380Application Date: 2013-10-14
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Publication No.: US09586950B2Publication Date: 2017-03-07
- Inventor: Scott D. Kuduk , Jason W. Skudlarek
- Applicant: MERCK SHARP & DOHME CORP. , Scott D. Kuduk , Jason W. Skudlarek
- Applicant Address: US NJ Rahway
- Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; John C. Todaro
- International Application: PCT/US2013/064754 WO 20131014
- International Announcement: WO2014/062533 WO 20140424
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/4545 ; C07D413/14 ; C07D401/12
Abstract:
The present invention is directed to 2-pyridyloxy-3-ester-4-nitrile compounds which are antagonists of orexin receptors. The present invention is also directed to uses of the 2-pyridyloxy-3-ester-4-nitrile compounds described herein in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds. The present invention is also directed to uses of these pharmaceutical compositions in the prevention or treatment of such diseases in which orexin receptors are involved.
Public/Granted literature
- US20150252033A1 2-PYRIDYLOXY-3-ESTER-4-NITRILE OREXIN RECEPTOR ANTAGONISTS Public/Granted day:2015-09-10
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