Invention Grant
US09586962B2 Disubstituted octahydropyrrolo [3,4-C] pyrroles as orexin receptor modulators
有权
二取代八氢吡咯并[3,4-C]吡咯作为食欲素受体调节剂
- Patent Title: Disubstituted octahydropyrrolo [3,4-C] pyrroles as orexin receptor modulators
- Patent Title (中): 二取代八氢吡咯并[3,4-C]吡咯作为食欲素受体调节剂
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Application No.: US14112712Application Date: 2012-04-20
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Publication No.: US09586962B2Publication Date: 2017-03-07
- Inventor: Michael A. Letavic , Dale A. Rudolph , Brad M. Savall , Brock T. Shireman , Devin Swanson
- Applicant: Michael A. Letavic , Dale A. Rudolph , Brad M. Savall , Brock T. Shireman , Devin Swanson
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agency: Baker & Hostetler LLP
- International Application: PCT/US2012/034372 WO 20120420
- International Announcement: WO2012/145581 WO 20121026
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D487/04 ; A61K31/421 ; C07D403/04 ; C07D413/10 ; C07D403/14 ; A61K31/498
![Disubstituted octahydropyrrolo [3,4-C] pyrroles as orexin receptor modulators](/abs-image/US/2017/03/07/US09586962B2/abs.jpg.150x150.jpg)
Abstract:
Disubstituted octahydropyrrolo[3,4-c]pyrrole compounds are described, which are useful as orexin receptor modulators. Such compounds may be useful in pharmaceutical compositions and methods for the treatment of diseased states, disorders, and conditions mediated by orexin activity, such as insomnia.
Public/Granted literature
- US20140171430A1 DISUBSTITUTED OCTAHYDROPYRROLO [3,4-C] PYRROLES AS OREXIN RECEPTOR MODULATORS Public/Granted day:2014-06-19
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