Invention Grant
- Patent Title: Antigen-specific T cell receptors and T cell epitopes
- Patent Title (中): 抗原特异性T细胞受体和T细胞表位
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Application No.: US13823079Application Date: 2011-09-19
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Publication No.: US09586997B2Publication Date: 2017-03-07
- Inventor: Ugur Sahin , Ozlem Tureci , Petra Simon , Tana Omokoko
- Applicant: Ugur Sahin , Ozlem Tureci , Petra Simon , Tana Omokoko
- Applicant Address: DE Mainz DE Mainz
- Assignee: BioNtech Cell & Gene Therapies GmbH,Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-Universitat Mainz gemeinnutzige GmbH
- Current Assignee: BioNtech Cell & Gene Therapies GmbH,Translationale Onkologie an der Universitatsmedizin der Johannes Gutenberg-Universitat Mainz gemeinnutzige GmbH
- Current Assignee Address: DE Mainz DE Mainz
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Priority: EP10009990 20100920; EP11000045 20110105
- International Application: PCT/EP2011/004674 WO 20110919
- International Announcement: WO2012/038055 WO 20120329
- Main IPC: C12N5/0783
- IPC: C12N5/0783 ; C07K14/005 ; A61K39/00 ; C07K14/47 ; C07K14/725 ; C07K14/705 ; C12N15/85 ; A61K39/12
Abstract:
The present invention relates to efficient methods for providing antigen-specific lymphoid cells. These lymphoid cells may be used to provide antigen specific T cell receptors having a defined MHC restriction and to identify immunologically relevant T cell epitopes. Furthermore, the present invention relates to antigen-specific T cell receptors and T cell epitopes and their use in immunotherapy.
Public/Granted literature
- US20130273647A1 Antigen-Specific T Cell Receptors and T Cell Epitopes Public/Granted day:2013-10-17
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