Invention Grant
- Patent Title: Chimeric antigen receptor and methods of use thereof
- Patent Title (中): 嵌合抗原受体及其使用方法
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Application No.: US15064938Application Date: 2016-03-09
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Publication No.: US09587020B2Publication Date: 2017-03-07
- Inventor: Chia-Yung Wu , James Onuffer , Wendell A. Lim
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic Field & Francis, LLP
- Agent Paula A. Borden; Otto C. Guedelhoefer
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C12N5/16 ; C07K16/28 ; C07K14/705 ; C07K16/18 ; C07K14/725 ; C12N9/90 ; A61K47/48 ; A61K35/17 ; C12N9/14 ; A61K39/00
Abstract:
The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided.
Public/Granted literature
- US20160185862A1 CHIMERIC ANTIGEN RECEPTOR AND METHODS OF USE THEREOF Public/Granted day:2016-06-30
Information query
