Invention Grant
- Patent Title: Polymeric structures containing strained cycloalkyne functionality for post-fabrication azidealkyne cycloaddition functionalization
- Patent Title (中): 含有应变环炔属功能性用于后制备叠氮炔环加成官能化的聚合物结构
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Application No.: US14418649Application Date: 2013-07-31
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Publication No.: US09587070B2Publication Date: 2017-03-07
- Inventor: Matthew Becker , Jukuan Zheng
- Applicant: Matthew Becker , Jukuan Zheng
- Agency: Renner Kenner Greive Bobak Taylor & Weber
- International Application: PCT/US2013/052971 WO 20130731
- International Announcement: WO2014/022535 WO 20140206
- Main IPC: C08G63/02
- IPC: C08G63/02 ; C08G63/91 ; C08G85/00 ; A61L27/14 ; A61L27/38 ; C07C271/34 ; C08G69/48 ; C08G63/685 ; C08G69/10 ; C08G63/00 ; D06M11/58 ; D01F6/60 ; D01F6/62
Abstract:
A method of creating biocompatible polymeric structures includes the steps of: providing a biocompatible polymer including a strained cycloalkyne end group; forming a polymeric structure from the biocompatible polymer such that the strained cycloalkyne end group remains on the biocompatible polymer; providing an azide tethered molecule; and, after forming the polymeric structure, reacting the azide tethered molecule with the cycloalkyne in an azide alkyne cycloaddition reaction to further functionalize the polymeric structure.
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