Invention Grant
US09587226B2 Method for the production of recombinant polyomaviral vector particles
有权
用于生产重组多重病毒载体颗粒的方法
- Patent Title: Method for the production of recombinant polyomaviral vector particles
- Patent Title (中): 用于生产重组多重病毒载体颗粒的方法
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Application No.: US13138913Application Date: 2010-04-22
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Publication No.: US09587226B2Publication Date: 2017-03-07
- Inventor: Walter Gerhardus De Vries
- Applicant: Walter Gerhardus De Vries
- Applicant Address: NL Leiden
- Assignee: Amarna Holding B.V.
- Current Assignee: Amarna Holding B.V.
- Current Assignee Address: NL Leiden
- Agency: TraskBritt, P.C.
- Priority: EP09158498 20090422
- International Application: PCT/EP2010/055330 WO 20100422
- International Announcement: WO2010/122094 WO 20101028
- Main IPC: C12N7/00
- IPC: C12N7/00 ; C12N5/07 ; C12N5/16 ; C12N5/00 ; C12N5/02 ; C12N15/00 ; C12P21/06
Abstract:
The present invention relates to improved methods for the production of viral particles, viral vector particles and recombinant proteins. In particular, the invention relates to improved methods for the production of recombinant polyomaviral vector particles and polyomaviral vector production cell lines. More in particular, the invention relates to methods for the production of simian polyomaviral vector particles such as simian virus 40 (SV40) viral vector particles. The invention also relates to compositions comprising viral vectors and uses thereof and viral vector particles to treat genetic disorders, transplant rejection, autoimmune diseases, infectious diseases, allergies or cancer. The invention also relates to methods for the production of recombinant proteins in mammalian cells and methods to enhance the production of recombinant proteins in mammalian cells.
Public/Granted literature
- US20120040399A1 METHOD FOR THE PRODUCTION OF RECOMBINANT POLYOMAVIRAL VECTOR PARTICLES Public/Granted day:2012-02-16
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