Invention Grant
US09587274B2 System and method for correcting primer extension errors in nucleic acid sequence data 有权
用于校正核酸序列数据中引物延伸误差的系统和方法

System and method for correcting primer extension errors in nucleic acid sequence data
Abstract:
An embodiment of method for correcting an error associated with phasic synchrony of sequence data generated from a population of substantially identical copies of a template molecule is described that comprises (a) detecting a signal generated in response to an incorporation of one or more nucleotides in a sequencing reaction; (b) generating a value for the signal; and (c) correcting the value for the phasic synchrony error using a first parameter and a second carry forward parameter.
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