Invention Grant
US09588122B2 Methods of treating cancer sensitive to anti-EGFR therapy and modifying treatment using peroxiredoxin 6 biomarker
有权
治疗对抗EGFR治疗敏感的癌症的方法和使用过氧氧化还原酶6生物标志物进行改良治疗
- Patent Title: Methods of treating cancer sensitive to anti-EGFR therapy and modifying treatment using peroxiredoxin 6 biomarker
- Patent Title (中): 治疗对抗EGFR治疗敏感的癌症的方法和使用过氧氧化还原酶6生物标志物进行改良治疗
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Application No.: US14206223Application Date: 2014-03-12
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Publication No.: US09588122B2Publication Date: 2017-03-07
- Inventor: Edwin Chang , Lingyun Xu , Nick Hughes , Carsten H. Nielsen , Sanjiv S. Gambhir , Parag Mallick , Arutselvan Natarajan
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Palo Alto
- Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
- Current Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
- Current Assignee Address: US CA Palo Alto
- Agency: Thomas | Horstemeyer, LLP
- Main IPC: G01N33/50
- IPC: G01N33/50 ; G01N33/574 ; A61K31/517 ; A61K31/5377

Abstract:
The present disclosure provides methods of treating cancer and modifying a cancer treatment for a cancer with an anti-EGFR drug by creating PRDX6 expression profiles and using the profiles to evaluate and optionally modify treatment. The present disclosure also provides assays and systems for assessing sensitivity of a cancer to an anti-EGFR therapy.
Public/Granted literature
- US20140275073A1 METHODS OF TREATING CANCER SENSITIVE TO ANTI-EGFR THERAPY AND MODIFYING TREATMENT USING BLOOD BIOMARKERS Public/Granted day:2014-09-18
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