Invention Grant
- Patent Title: Intranasal administration of ketamine to treat depression
- Patent Title (中): 氯胺酮鼻内给药治疗抑郁症
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Application No.: US14306382Application Date: 2014-06-17
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Publication No.: US09592207B2Publication Date: 2017-03-14
- Inventor: Dennis S. Charney , Sanjay J. Mathew , Husseini K. Manji , Carlos A. Zarate , John H. Krystal
- Applicant: Icahn School of Medicine at Mount Sinai , Yale University , The United States of America, as represented by the Secretary, Department of Health and Human Services
- Applicant Address: US NY New York US CT New Haven US DC Washington
- Assignee: Icahn School of Medicine at Mount Sinai,Yale University,The United States of America, as represented by The Secretary, Department of Health and Human Services
- Current Assignee: Icahn School of Medicine at Mount Sinai,Yale University,The United States of America, as represented by The Secretary, Department of Health and Human Services
- Current Assignee Address: US NY New York US CT New Haven US DC Washington
- Agency: Fish & Richardson P.C.
- Main IPC: A61K31/135
- IPC: A61K31/135 ; A61K9/00 ; A61K9/70 ; A61K31/137 ; A61K45/06 ; A61M15/08
Abstract:
Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (>2 years).
Public/Granted literature
- US20150056308A1 INTRANASAL ADMINISTRATION OF KETAMINE TO TREAT DEPRESSION Public/Granted day:2015-02-26
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