Invention Grant
- Patent Title: Use of pan-PPAR agonists for treatment of tauopathies
- Patent Title (中): 使用泛PPAR激动剂治疗tau蛋白病
-
Application No.: US14274025Application Date: 2014-05-09
-
Publication No.: US09592212B2Publication Date: 2017-03-14
- Inventor: Flint Beal
- Applicant: Cornell University
- Applicant Address: US NY Ithaca
- Assignee: Cornell University
- Current Assignee: Cornell University
- Current Assignee Address: US NY Ithaca
- Agency: Sutherland Asbill & Brennan LLP
- Main IPC: A61K31/195
- IPC: A61K31/195 ; A61K31/19 ; A61K45/06 ; A61K31/192
Abstract:
The present invention provides a therapeutic treatment for a neurodegenerative disease with a pan-PPAR agonist, such as bezafibrate. In particular, the present invention provides that pan-PPAR agonists enhance PPAR related responses in both the central nervous system and peripheral tissues in Huntington's Disease (HD) and tauopathy. Therapeutic compositions comprising one or more pan-PPAR agonist(s), and kit thereof, for treating a neurodegenerative disease or disorder are also provided.
Public/Granted literature
- US20140350107A1 Use of Pan-PPAR Agonists for Prevention and Treatment of Huntington's Disease and Tauopathies Public/Granted day:2014-11-27
Information query
