A fuel management module for use with a CNG fuel system for a vehicle includes a housing configured to be connected to the vehicle and a number of connections, receptacles, and controls associated with the module. A defueling receptacle may be positioned on the front panel of the housing, for defueling a fuel tank of the vehicle. A defueling control valve may be positioned on the front panel of the housing for controlling operation of the defueling receptacle, allowing for selective defueling. One or more high pressure connections may be accessible on the housing and configured for connection to one or more separate fuel tanks in a plug and play configuration. A plurality of filling connections may be accessible on the housing for filling the fuel tank(s). A low pressure fuel output connection may be positioned on the back panel of the housing to provide fuel output from the high pressure connections to the engine.