Invention Grant
US09593127B2 Heterocyclylalkyne derivatives and their use as modulators of mGluR5 receptors
有权
杂环炔基衍生物及其作为mGluR5受体调节剂的用途
- Patent Title: Heterocyclylalkyne derivatives and their use as modulators of mGluR5 receptors
- Patent Title (中): 杂环炔基衍生物及其作为mGluR5受体调节剂的用途
-
Application No.: US14983277Application Date: 2015-12-29
-
Publication No.: US09593127B2Publication Date: 2017-03-14
- Inventor: Carlo Riva , Carlo De Toma , Patrizia Angelico , Elena Poggesi , Davide Graziani
- Applicant: RECORDATI IRELAND LTD.
- Applicant Address: IE
- Assignee: RECORDATI IRELAND LTD.
- Current Assignee: RECORDATI IRELAND LTD.
- Current Assignee Address: IE
- Agency: Leason Ellis LLP
- Main IPC: C07D498/04
- IPC: C07D498/04 ; A61K31/424
Abstract:
This invention relates to compounds of formula I, their use as allosteric modulators of mGluR5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for the treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction, such as schizophrenia or cognitive decline, dementia or cognitive impairment, or other pathologies that can be related directly or indirectly to glutamate dysfunction.
Public/Granted literature
- US20160185798A1 HETEROCYCLYLALKYNE DERIVATIVES AND THEIR USE AS MODULATORS OF mGluR5 RECEPTORS Public/Granted day:2016-06-30
Information query
