Invention Grant
US09593139B2 Compositions, methods, and kits comprising platinum compounds associated with a ligand comprising a targeting moiety
有权
包含与包含靶向部分的配体相关的铂化合物的组合物,方法和试剂盒
- Patent Title: Compositions, methods, and kits comprising platinum compounds associated with a ligand comprising a targeting moiety
- Patent Title (中): 包含与包含靶向部分的配体相关的铂化合物的组合物,方法和试剂盒
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Application No.: US14245360Application Date: 2014-04-04
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Publication No.: US09593139B2Publication Date: 2017-03-14
- Inventor: Stephen J. Lippard , Justin J. Wilson , Robert John Radford , Maria R. Chan , Daniel Y. Zhang
- Applicant: Massachusetts Institute of Technology
- Applicant Address: US MA Cambridge
- Assignee: Massachusetts Institute of Technology
- Current Assignee: Massachusetts Institute of Technology
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C07F15/00
- IPC: C07F15/00

Abstract:
Compositions, kits, and methods for treatment of cancers are generally provided. In some embodiments, the compositions, kits, and methods comprise a platinum (e.g., Pt(II) or Pt(IV)) compound associated with a ligand (e.g., a beta-diketonate ligand) comprising a targeting moiety. Methods of synthesizing platinum (e.g., Pt(II) or Pt(IV)) compounds associated with a ligand comprising a targeting moiety are also provided.
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