Invention Grant
US09593318B2 Linker-bridged gene or domain fusion reverse transcriptase enzyme 有权
链接桥连基因或结构域融合逆转录酶

  • Patent Title: Linker-bridged gene or domain fusion reverse transcriptase enzyme
  • Patent Title (中): 链接桥连基因或结构域融合逆转录酶
  • Application No.: US13870842
    Application Date: 2013-04-25
  • Publication No.: US09593318B2
    Publication Date: 2017-03-14
  • Inventor: Jun Euihum Lee
  • Applicant: Jun Euihum Lee
  • Agency: East West Law Group
  • Agent Heedong Chae
  • Main IPC: C12N9/12
  • IPC: C12N9/12 C12N9/22
Linker-bridged gene or domain fusion reverse transcriptase enzyme
Abstract:
The present invention relates to combinations of a linker bridged gene or domain fusion reverse transcriptase enzyme, and more particularly, combinations of a linker bridged gene or domain fusion reverse transcriptase enzyme and their fusion construction utilizing for more efficient and quality DNA synthesis in reverse transcription. The composition of the invention includes a polymerase domain; a linker, consisting of 3-40 amino acids; and an RNase H domain, wherein the RNase H domain is either unmodified or modified with point mutations. The composition may further include another mutated RNase H, a mutated RNase A, and an additional linker which consists of 3-40 amino acids.
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