Invention Grant
- Patent Title: Linker-bridged gene or domain fusion reverse transcriptase enzyme
- Patent Title (中): 链接桥连基因或结构域融合逆转录酶
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Application No.: US13870842Application Date: 2013-04-25
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Publication No.: US09593318B2Publication Date: 2017-03-14
- Inventor: Jun Euihum Lee
- Applicant: Jun Euihum Lee
- Agency: East West Law Group
- Agent Heedong Chae
- Main IPC: C12N9/12
- IPC: C12N9/12 ; C12N9/22

Abstract:
The present invention relates to combinations of a linker bridged gene or domain fusion reverse transcriptase enzyme, and more particularly, combinations of a linker bridged gene or domain fusion reverse transcriptase enzyme and their fusion construction utilizing for more efficient and quality DNA synthesis in reverse transcription. The composition of the invention includes a polymerase domain; a linker, consisting of 3-40 amino acids; and an RNase H domain, wherein the RNase H domain is either unmodified or modified with point mutations. The composition may further include another mutated RNase H, a mutated RNase A, and an additional linker which consists of 3-40 amino acids.
Public/Granted literature
- US20140322789A1 LINKER-BRIDGED GENE OR DOMAIN FUSION REVERSE TRANSCRIPTASE ENZYME Public/Granted day:2014-10-30
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